---You look upset. Anything wrong?
---I failed in the physics exam again ______ all the efforts I made.

1. A.
   in spite of
2. B.
   despite
3. C.
   but for
4. D.
   regardless of

--You look upset.  Anything wrong?
--I failed in the physics exam again _____all the efforts I made

1. A.
   because of
2. B.
   for once
3. C.
   even if
4. D.
   despite

--You look upset.  Anything wrong?

 --I failed in the physics exam again _____all the efforts I made.

A. because of          B. for once        C. even if       D. despite

--You look upset.  Anything wrong?
--I failed in the physics exam again _____all the efforts I made.

—You look upset. Anything wrong?

－I failed in the physics exam again ________ all the efforts I made.

Which of the following answers is NOT true？