However _____ they are designed, pens should function as a tool to write with.
A．differB．differenceC．differentD．differently
D
句意：無論鋼筆被設(shè)計的多么不同，他們的作用還是作為書寫用的工具。However后修飾形容詞或副詞，根據(jù)語境應(yīng)用副詞修飾動詞，所以用differently，選D。
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