________ lack of interest, Tom kept trying hard to catch up with others.
A．AlthoughB．In spiteC．ThoughD．Despite
D
考查詞義辨析。Although與Though 是連詞，后需要跟從句，In spite 后加of構(gòu)成短語，盡管，Despite 為介詞，盡管，句意：盡管缺乏興趣，湯姆為了趕上別人他繼續(xù)努力。所以選D。
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